A PCP once told me, diabetes patients are one of the hardest groups to adhere to their treatment plans because diabetes doesn\u2019t cause immediate or intense pain. On the IT side, the equivalent is the \u201cnice to have\u201d technology. You will need your computers, storage, security, EMR, etc. but what the minimum investment you should make is, if at all, in advanced technology like artificial intelligence (AI) is much harder to answer.\nIn a report published recently by HHS, Artificial Intelligence for Health and Health Care, the organization tasked with the study, JASON (an independent group of scientists and academics that has been advising the Federal government on matters of science and technology for over 50 years), concluded that \u201cunlike previous eras of excitement over AI, the potential of AI applications in health may make this era different\u2026\u201d The report also concluded \u201cAI is beginning to play a growing role in transformative changes now underway in both health and health care, in and out of the clinical setting. At present the extent of the opportunities and limitations is just being explored.\u201d It means the innovators and some early adopters are in, and whether to invest depends on what position on the adoption curve you want to play.\nAccenture\u2019s whitepaper, Artificial Intelligence: Healthcare\u2019s New Nervous System, lists the top 10 AI applications in healthcare, and estimated their near-term values in terms of annual benefits. The top 3 are robot-assisted surgery ($40B), virtual nursing assistants ($20B) and administrative workflow assistance ($18B). While pondering whether those broad categories should be the areas of your focus, or to increase investments in them, it may be beneficial to take a look at what others are doing.\nData management: the first step, and commonality\nOne community hospital, for instance, used unsupervised machine learning and supervised prediction to reveal optimal care pathways for pneumonia by identifying the commonalities between those with the best outcomes among thousands of patient records. The effort started with using SQL code to pull data from multiple hospital systems (AllScripts EHR, enterprise data warehouse, surgical, financial and corporate performance), and FHIR to deliver the results into the clinical variation management application. With the help of an intuitive interface that reveals insights (e.g. the reason, and timing, for a recommended pathway step), the project garnered sufficient support to deploy the optimal care pathway by revising the ED and inpatient order sets in the EHR. This initial work on pneumonia care pathway saved $850,000 in unnecessary costs. Now sepsis, heart failure, total hip replacement and COPD are among others on the horizon.\nMontefiore Health System took a more fundamental approach: developing a data lake, and graph-database based infrastructure that may support a variety of patient-care use cases. It has enabled them to implement advanced sepsis detection tools, and also tools to support clinical decision making at the point of care. The investment in data management pays off well: their data scientists now spend 70% of time doing AI analytics vs. 75% in data management and data wrangling previously. The resulting infrastructure, Patient-centered Analytical Learning Machine (PALM), becomes the foundation that brings economies of scale to AI analytics projects.\nBeside supports in the organizations, common to both projects is data integration. AI starts with data, and data management (via data governance, cleansing, ETL, semantic harmonization and others) efforts provide the foundation on which AI algorithms can source semantically harmonized data, build models, make predictions and refine models. It is also necessary to bring the results to the healthcare workflows \u2013 e.g. revising order sets, or injecting insights into point-of-care system \u2013 to realize the benefits.\nOnce you have data management down, plenty of opportunities exist for AI as tools to support innovations that will bring much ROI to the organization. For example, a combination of Natural Language Processing and Artificial Neural Network can easily surface misses in insurance verification and\/or preauthorization so the care team can get them straightened out prior to an encounter for a procedure.\nAI-augmented analytics\nWith that, the initial focus is back to data-driven initiatives, and providing the insights \u2013 be it from AI, BI (business intelligence, like OLAP and data visualization tools) or humans (e.g., case management) \u2013 to the frontline workers in order to guide decision making and\/or automate work, without which the AI investments will have limited impacts. Gartner called this \u201caugmented analytics\u201d in its Gartner Top 10 Strategic Technology Trends for 2019 Smarter with Gartner article. \u201cAugmented analytics represents a third major wave for data and analytics capabilities as data scientists use automated algorithms to explore more hypotheses. Data science and machine learning platforms have transformed how businesses generate analytics insight,\u201d according to David Cearley, vice president and Gartner Fellow.\nKai-Fu Lee, an AI expert, venture capitalist and the author of \u201cAI Superpowers: China, Silicon Valley and the New World Order,\u201d portrayed a very broad-based, cross-industry, cross-geography view of AI\u2019s impacts. A point Lee put forth to argue the China advantage is that good, widely adopted products generate a detailed treasure trove of data, which in turns allows companies to perform sophisticated AI to produce better and more widely adopted products. The virtuous cycle continues, and the industry leaders that do this well will keep widening their leads over others, resulting in winner-take-all economics.\nThen the minimum winning AI strategy is managing data to enable AI explorations. The work product of the strategy may facilitate many projects that use data to lead to better services, implement better services to bring more patients and start the virtuous cycle.