Health Care IT: The Right Dose of Technology Helps the Medicine Go Down

As a medical resident at the Hospital of the University of Pennsylvania (UPenn), Dr. Scott Halpern spent hours at his hospital’s computer terminals searching for the right tests and medications for his patients. But Halpern would often become so frustrated with the system—which was slow and required specific language for each request—that he would give up and stop using the system when he could find another way to take care of the patient.

Halpern is much happier with his hospital’s newer, more user-friendly order-entry system. But he still sees problems. One of the biggest, he says, is the annoying alerts that constantly pop up onscreen as he orders a patient’s dosage. "I honestly haven’t paid attention to a pop-up alert in years," says Halpern, who like many doctors believes that alerts should be limited only to those that might help avoid a serious medical error. "I just click right through them as quickly as possible and I think most doctors do the same thing," he says.

Those pesky alerts were designed to prevent medication errors, but because they pop up so often, many are ignored. Halpern’s frustration with such a poorly designed feature reflects an ongoing struggle with computerized drug-order systems at hospitals across the country. Computerized physician order-entry, commonly known as CPOE, holds great promise to improve patient safety as it radically changes the way that doctors, nurses and hospital employees do their jobs. CPOE is still in its early phases—only 4 percent of U.S. hospitals are using the systems according to consultancy Klas Enterprises—but research shows it can improve patient safety. Studies at Brigham and Women’s Hospital, where informatics leaders developed their own system in the 1990s, revealed that CPOE cut medication errors by 80 percent. And nationwide adoption of CPOE could save $44 billion a year in reduced costs from radiology, laboratory and medication errors, according to a study by the Center for Information Technology Leadership.

Doctors such as Halpern agree the new systems are superior to the pen-and-paper method of prescribing medication, which can lead to misunderstandings and transcription errors. But early experiences with CPOE show that success involves much more than plugging in the software. Those at the forefront of CPOE adoption agree that systems are expensive and difficult to implement in hospital environments. And a recent study performed at UPenn raised alarm by claiming that CPOE can actually increase the potential for medical errors. Indeed, experts agree that CPOE can introduce new risks if not designed and implemented correctly, or does not fit in smoothly with a hospital’s particular "work flow." CIOs ready to invest millions of dollars in CPOE need to make sure that IT staff work closely with their medical counterparts to design the systems and provide extensive training for those who will use it. They should also partner with their vendor to customize the system for their own specific needs. And CIOs need to monitor the CPOE closely to make sure that glitches are fixed before they can cause unexpected medication errors.

CPOE projects are like many tricky enterprisewide implementations, and CIOs from health care and other industries can learn important lessons about change management from hospitals that have gotten CPOE right, including Brigham and Women’s, Duke University Medical Center and Health System, Intermountain Health Care in Utah, and St. Joseph Health System in Orange County, Calif.

"The simple truth is that CPOE is not a turnkey solution," says Brian Strom, chair of the department of biostatistics and epidemiology at the UPenn medical school. "Getting it right takes a tremendous amount of monitoring and tailoring. No one expected Word 1.0 to be perfect, so it’s not surprising that CPOE 1.0 isn’t perfect either."

To Err Doesn’t Have to Be Human

Until the turn of the 21st century, only a few major hospitals had attempted to design and implement CPOE systems. But then in November 1999, the Institute of Medicine published a report that galvanized the nation’s medical community. The report, "To Err Is Human," put forth some disturbing figures. Avoidable medical mistakes kill anywhere from 44,000 to 98,000 people a year—more than breast cancer, highway accidents or AIDS. The report also said that more than 7,000 deaths are caused by medication errors.

CPOE quickly rose to the forefront of health IT systems as a promising means of preventing medical errors. Large vendors such as Cerner and McKesson developed and updated CPOE systems, and hospitals large and small began to adopt the new technology. The road has not always been smooth for those adopting the systems, however. In January 2003, in a high-profile case that spooked the medical world, doctors at Cedars-Sinai Medical Center in Los Angeles, unhappy with the extra time it took them to enter orders on the computer, staged a rebellion and forced the hospital to shelve the CPOE portion of a $32 million implementation project after three months of use. Then, in March of this year, researchers at UPenn published a study in the Journal of the American Medical Association (JAMA) documenting that their CPOE system, an early model from Eclipsys, could cause 22 types of medication error risks.

The researchers, led by Ross Koppel, a sociology professor at the UPenn School of Medicine, surveyed staff using the CPOE and shadowed doctors, nurses and IT staff to see how they used the system. One risk discussed in the study was the difficulty staff had in discerning which patients the doctor was ordering for, because the CPOE display was fragmented and required switching between multiple screens. Such clunky features increased the risk for faulty orders on a regular basis, the study found.

The UPenn study generated heated discussion and dozens of editorials in medical journals. Critics castigated the study for failing to compare data from the pen-and-paper era and for focusing on what many consider an out-of-date system that is not representative of systems widely in use today. But CPOE experts say that, nonetheless, the study highlighted some important truths about the difficulty of implementing CPOE. And the UPenn researchers say that more recent studies on a newer system show that while the doctors and nurses prefer it to the former system, the new system has not solved all the original problems that could lead to medication errors. Most notably, the structure and format of the screens can still cause medical staff to prescribe drugs for the wrong patient, the researchers say.

All of this debate comes as hospitals are facing increasing pressure from the government and patient safety groups to install systems such as CPOE and electronic medical records (EMRs), which replace paper files by placing medical and patient records on a computerized system. The U.S. Medicare system recently announced plans to offer lower-priced medical records software to doctors. (See "Feds Sweeten the Pot" on Page 80.) So far, slow adoption of CPOE and EMRs has been attributed to lack of funding and physician resistance. The difficult experience at Cedars-Sinai highlights the scope and amount of preparation needed to implement large-scale clinical systems. A move to CPOE can have a serious impact on the way that doctors and nurses do their work, and those hospitals that have been successful with CPOE have worked to avoid the kinds of disruptions that have made clinicians shy away from using the systems.

"CPOE will be the biggest clinical change initiative most hospitals have ever undertaken," says Dr. David Classen, who helped design the CPOE system at Intermountain Health Care in Salt Lake City and is now a consultant on CPOE to The Leapfrog Group, a Washington, D.C.-based health-care consortium.

How to Get It Right the First Time

Hospitals going through this massive change need to first focus on how doctors do their work to avoid inconveniencing them with additional tasks, says Asif Ahmad, CIO of Duke University Medical Center and Health System. Ahmad, who implemented CPOE at Ohio State University before coming to Duke, says the key to success lies in working closely with the doctors and nurses to help design the system, even if using vendor-built software. At Duke, Ahmad cochaired the CPOE task force with the hospital’s chief medical officer, and within his IT department, there are six physicians as well as 30 nurses and four pharmacists reporting to him. "It’s imperative that CIOs in hospitals build technical and clinical teams," he says. "People responsible for building or overseeing CPOE systems need to understand the clinical system." Although Duke bought its CPOE system from McKesson, doctors helped customize it to fit in with their way of doing things. When a doctor or nurse clicks a button to admit a cardiac patient, for example, the system shows them tasks and treatments such as administering aspirin.

"If physicians help design CPOE, and it’s done the right way, it’s not going to cause errors," Ahmad says.

Duke’s CPOE system, which went fully live on all 590 patient beds as of June 20, includes 259 "order sets," specific instructions for standard medical procedures that were jointly developed by physicians. "The idea was to get all the cardiologists in one room and tell them they can’t leave until we agree on a set of directions on how to manage patients," he says. "Sometimes there are personal preferences but we have to agree to make the system work." During the first nine months of the process, he held regular meetings with doctors and nurses to map workflow for each speciality and unit of the hospital. As a result of these meetings and close consultation with medical staff, the team of doctors and IT staff were able to avoid design problems they viewed as potentially harmful to patient safety. For example, the design team made sure that information on a single patient remains on the same page or screen and staff cannot swing to another patient’s page until the orders have been completed for the initial patient. "If you display more than one patient on the same screen, you have a greater potential for error," Ahmad says.

Ahmad also says doctor input pushed the IT team to create a "single sign-on," which allows physicians to look at test results on one system and then move into the CPOE system without having to log out and log in again. And in order to combat "alert fatigue," Ahmad says Duke is working on building a corollary system that will send most alerts outside of CPOE. Then, doctors will be able to do their work without the nuisance of constant pop-ups telling them about interactions that are not dangerous to the patient. A select group of pharmacists, doctors and nurses monitoring this corollary system will be able to respond to serious alerts.

Big Bang Versus Gradual Approach

Benjamin R. Williams, CIO and senior VP of strategic innovation at St. Joseph Health System, an hour south from L.A., agrees that a close relationship with the medical staff is key to CPOE success. Williams watched closely as doctors rejected the system at nearby Cedars-Sinai and has carefully structured the CPOE initiative at his own network of community hospitals to involve doctors from the start. He designated champions of the system among the medical staff to convince more reluctant doctors to use the system. He also decided to phase the CPOE rollout over a period of several years and encourage doctors to use it, rather than force them to do so all at once, which is what Cedars-Sinai did. Phasing it in has also allowed his team to make fixes and respond to doctors’ concerns about the system’s design.

Dr. Thomas Hughes, an ob-gyn specialist at St. Jude Hospital, a part of the St. Joseph Health System, has served as a kind of liaison between doctors and IT staff. At one point, Hughes brought together a team of 41 doctors to help design the system, working with vendor Meditech. At St. Jude, 40 percent of admissions are now done using the system that includes CPOE, and about 60 doctors out of 280 are using the system regularly. A larger number use the system to check lab results, and Hughes hopes that he and his team will gradually be able to convince the rest to use computerized drug-ordering. Hughes said that by bringing in doctors who showed interest in using the system first, the hospital has been able to get started in a gradual and more positive way. Then, as the first enthusiastic doctors get used to the system, they will, he hopes, be able to convince more reticent ones to join them.

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