Nothing ever changes in the cloud, right? That might seem to be the case if, say, a company starts using Box for sales presentations or relying on one of the many online accounting packages that works from anywhere and manages the security for you. Many of these systems are maturing and don't make radical improvements \u2014 and that's often a good thing.However, innovations do pop up. Many, including the six discussed below, could impact your business this year.Genetic SequencingUsing powerful supercomputers to help with cancer research isn't exactly new \u2014 but moving the scientific calculations to the cloud marks a major undertaking. Analyst Charles King says this is a significant project in two major ways: One, it's try to understand the genomic sequencing that occurs in brain cancer patients, and two, it's showing how the cloud is maturing. The cloud-based version of IBM Watson can scan databases and learn how to customize treatments to patient DNA.\n\n[ News: IBM Watson Has Another Go at Solving Brain Cancer Riddles ]\n[ Analysis: How Genomic Research Could Improve Healthcare ]Microsoft Office 365 for iPad(Screen shot courtesy of Microsoft.)This advancement might not seem that world-changing, although it's surprising that Microsoft has finally launched Office apps on the Apple iPad. What is game-changing for business users: The apps sync securely to the cloud. The apps are also free for business users who've already standardized on Office 365 and pay the monthly Web usage storage fees. Importantly, the apps were designed for tablet use, meaning they support swiping and other gestures.\n\n[ News: Microsoft (Finally) Unveils Office for iPad ]\n[ Commentary: Why Microsoft Office for iPad was Worth the Wait ]Basic6Using a console to manage cloud servers and data center services in one view lets you accomplish tasks such as managing accounts, setting passwords and controlling Amazon Elastic Compute Cloud (EC2) features. The main innovation with Basic6, though, is that the dashboard works in real-time for services such as Box and AWS at the same time. Most features are managed using a tree structure on the left pane. The console maintains an audit trail of exactly which changes were made to which cloud services.\n\n[ Commentary: Manage Cloud Computing With Policies, Not Permissions ]\n[ More: 10 Cloud Administration Must-Haves You Can't Have Yet ]Box ViewWriting code for the cloud might be about as dull as a routine health exam, but Box is making it as easy as possible. One innovation, Box View, essentially gives even nonprogrammers a way to upload a business document and create rich HTML sites with an embedded document viewer. It's also a sign of things to come \u2014 that is, the cloud will continue to evolve in terms of developing custom apps and features that match business needs.\n\n[ Commentary: How DevOps Can Accelerate the Cloud Application Lifecycle ]\n[ Tips: 6 Ways the Cloud Enhances Agile Software Development ]Amazon WorkSpacesOffering a virtual desktop to employees has always presented one great IT challenge: Making sure the desktop is always available and tuned for speedy performance. Amazon recently started offering WorkSpaces, a cloud-based desktop that runs on laptops and tablets. The main innovation of Amazon WorkSpaces concerns network optimization using Amazon Web Services; this provides the same kind of availability you've come to expect from a cloud storage service or custom application.\n\n[ News: Amazon Workspaces Becomes Generally Available ]\n[ Feature: 5 More Desktops in the Cloud ]SmartVueVideo surveillance in a corporate setting is a different beast from home surveillance; there are likely policies about encrypting the signal, storing the recorded video and managing the cameras, among other things. The Smartvue cloud surveillance servers lets you view and manage cameras from a Web browser. Security cameras installed on premises can link to the cloud server for policy management, storage and security controls \u2014 and many third-party cameras will work just fine.\n\n[ Tips: How to Deploy IP Cameras in Your Small Business ]\n[ More: The Basics of Video Surveillance and Data Monitoring ]John Brandon is a former IT manager at a Fortune 100 company who now writes about technology. He has written more than 2,500 articles in the past 10 years. You can follow him on Twitter @jmbrandonbb. Follow everything from CIO.com on Twitter @CIOonline, Facebook, Google + and LinkedIn.