A new weapon in the battle against cancer: artificial intelligence

A leading European cancer research and care center validates the opportunity to use artificial intelligence to predict the response to immunotherapy.

Dell EMC

In today’s hospitals and healthcare clinics, a new doctor’s new assistant is now often on the job — in the form of artificial intelligence. Whether it’s analyzing medical images or guiding robots that assist with surgeries, AI is making steady inroads into our hospitals and clinics. Need an online nursing assistant or a watchdog that helps detect dosage errors? There’s an AI application for that.

The advent of AI in healthcare is a promising trend in terms of both patient care and economic efficiency. AI can help us address a forecasted shortage of physicians, particularly in specialty-care fields, while containing the costs of caring for an aging and growing population.[1] A recent study by a team of researchers from the consulting firm Accenture found that the use of 10 promising AI applications could create up to $150 billion in annual savings for U.S. healthcare by 2026.[2]

For an example of the potential of AI in healthcare, we need to look no further than Gustave Roussy, a leading European center for cancer research and care. In a study published this summer in the medical journal The Lancet Oncology, a team of medical researchers from Gustave Roussy and a few other institutions demonstrated that AI can process medical images to extract biological and clinical information to help with immunotherapy treatment, according to a news release on the study.[3]

In this groundbreaking study, the researchers used an algorithm they designed and developed to analyze CT scan images and create a “radiomic signature.” This signature defines the level of lymphocyte infiltration of a tumor — or the degree to which immune cells have moved from the blood into a tumor cell. The radiomic signature also provides a predictive score for the efficacy of immunotherapy in the patient.

Here’s how AI played into this research: Using an approach based on machine learning, the team first taught the algorithm to use relevant information extracted from CT scans of patients participating in the study. Then, based solely on images, the algorithm learned to predict what the genome might have revealed about the tumor immune infiltrate, and it established the radiomic signature.   

The announcement summarizing the findings of the study notes that in the future, physicians might be able to use imaging to identify biological phenomena in a tumor located in any part of the body without having to perform a biopsy.

At Dell EMC, this research is particularly close to our hearts because we are active supporters of Gustave Roussy. The Paris-based cancer center is one of nine partner organizations within the Dell EMC Children’s Cancer Care program. This global initiative — part of the Dell EMC Sponsorships and Giving program — involves a multimillion dollar commitment that covers both technology and volunteering by Dell EMC employees. Through it, Dell EMC has provided technology to Gustave Roussy that powers classrooms so that children can continue with their education while receiving treatment.

Dell EMC also provides a lot of technology that helps Gustave Roussy stay at the leading edge of cancer research and care. That technology includes the Intel-based Dell EMC HPC System for Life Sciences, which the cancer center is using for a genomic data analysis platform. That platform has helped Gustave Roussy run eight times more analyses on genome deterioration in a single day — to accelerate research into pediatric cancers and reduce patient waiting lists. [4]

For a closer look at the great things Gustave Roussy is doing with Dell EMC systems, read the case study “Cancer centre speeds up life-saving treatments” or watch the video “Gustave Roussy improves pediatric cancer treatments by speeding genomic analysis with Dell servers.”

[1] Association of American Medical Colleges (AAMC), “GME Funding and Its Role in Addressing the Physician Shortage,” May 29, 2018.

[2] Brian Kalis, Matt Collier, Richard Fu, “10 Promising AI Applications in Health Care,” Harvard Business Review, May 10, 2018.

[3] Gustave Roussy news release, “Predicting the response to immunotherapy using artificial intelligence,” August 27, 2018.

[4] Dell EMC case study, “Cancer centre speeds up life-saving treatments,” August 2017.

Copyright © 2018 IDG Communications, Inc.